The 33-year-old is suffering from a hamstring injury which had seen him struggling ahead of the first leg two weeks ago.
According to reports in Spain, Xavi is unlikely to be fit for the return leg at the Camp Nou on March 12.
Blaugrana must overcome a 2-0 deficit if they are to reach the quarter-finals.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Real Madrid | 32 | 25 | 6 | 1 | 70 | 22 | 48 | 81 |
| 2 | Barcelona | 32 | 21 | 7 | 4 | 64 | 37 | 27 | 70 |
| 3 | GironaGirona | 32 | 21 | 5 | 6 | 67 | 40 | 27 | 68 |
| 4 | Atletico MadridAtletico | 32 | 19 | 4 | 9 | 59 | 38 | 21 | 61 |
| 5 | Athletic Bilbao | 32 | 16 | 10 | 6 | 52 | 30 | 22 | 58 |
| 6 | Real Sociedad | 32 | 13 | 12 | 7 | 46 | 34 | 12 | 51 |
| 7 | Real BetisBetis | 32 | 12 | 12 | 8 | 40 | 38 | 2 | 48 |
| 8 | Valencia | 32 | 13 | 8 | 11 | 35 | 34 | 1 | 47 |
| 9 | Villarreal | 32 | 11 | 9 | 12 | 51 | 55 | -4 | 42 |
| 10 | Getafe | 32 | 9 | 13 | 10 | 38 | 44 | -6 | 40 |
| 11 | Osasuna | 32 | 11 | 6 | 15 | 37 | 46 | -9 | 39 |
| 12 | Sevilla | 32 | 9 | 10 | 13 | 41 | 45 | -4 | 37 |
| 13 | Las PalmasLas Palmas | 32 | 10 | 7 | 15 | 30 | 39 | -9 | 37 |
| 14 | AlavesAlaves | 32 | 9 | 8 | 15 | 28 | 38 | -10 | 35 |
| 15 | Rayo Vallecano | 32 | 7 | 13 | 12 | 27 | 39 | -12 | 34 |
| 16 | Celta Vigo | 32 | 7 | 10 | 15 | 37 | 47 | -10 | 31 |
| 17 | Mallorca | 32 | 6 | 13 | 13 | 26 | 38 | -12 | 31 |
| 18 | CadizCadiz | 32 | 4 | 13 | 15 | 22 | 45 | -23 | 25 |
| 19 | Granada | 32 | 3 | 9 | 20 | 33 | 61 | -28 | 18 |
| 20 | Almeria | 32 | 1 | 11 | 20 | 31 | 64 | -33 | 14 |
| > La Liga Full Table | |||||||||
