Enrique represented the Catalan outfit as a player from 1996 until 2004, before taking charge of the B team for three years from 2008.
However, the Spaniard returns to the Camp Nou this evening looking to put one over on his former club in La Liga.
"It's been 10 years since I retired as a player and this is my first time back. It's a stadium, a city and a group of fans I consider most special," he told reporters at a press conference.
"I'll be back among family, so it'll be a special occasion for me. What we'll need is for Barca to have a bad day. There's only one ball and I'm afraid Barca will have it, which happens to all teams they face.
"The Barca squad is powerful and whoever plays is good. It's possible to stop Messi. We'll have to defend against him however we can, with a stopper and someone to cover. Against a player who is capable of dribbling past three players in three metres... how do you stop that?"
Celta currently sit 12th in La Liga.