The Spain international has been accused of play-acting in the past, while Neymar was criticised by Celtic boss Neil Lennon for his part in Scott Brown's dismissal during the Blaugrana's recent win in Glasgow.
"Play-acting? It's not play-acting, it's being smart," Busquets told Spanish radio station Cadena COPE.
"It's a debate we shouldn't be having because that's not the real issue. It's all too easy to label people."
Busquets has made eight appearances for Barcelona this season.