The home side currently sit 19th in the table, but are just two points behind 17th-placed Osasuna, who sit one spot and one place above Deportivo La Coruna.
Atletico's chances of finishing second have all but evaporated in recent weeks, however, with rivals Real Madrid now eight points clear of their capital rivals as we enter the latter stages of the season.
It was Atletico that were 1-0 winners in the reverse match earlier in the season, but that was the only time in the last five years that the pair have met in the top division of Spanish football.
Celta have won six of their 17 matches on their own patch this season, which is the most out of the teams around them. However, Atletico have the third-strongest away record in the league, taking 26 points from 17 matches.
Atletico, meanwhile, could welcome back Arda Turan to their starting side, with Diego Costa also expected to return to the team. Should those changes take place, Cristian Rodriguez and Adrian Lopez could drop to the bench.
Celta: Varas; Arceo, Bellvis, Johny, Oubina; Vila, Lopez, Fernandez, Madinda; Aspas, Bermejo
Atletico: Courtois; Juanfran, Godin, Miranda, Luis; Suarez, Garcia, Gabi; Costa, Falcao, Turan
Sports Mole says: 1-2