With just seven La Liga games remaining, Atletico currently top the Spanish table, while they will tackle Barcelona in the quarter-finals of the Champions League.
However, Koke has avoided talk of winning La Liga and branded every game "a cup final".
"Until there are five games left, we won't talk about the title," Koke told reporters.
"The sky's the limit for Atleti. Every game is a cup final. On Tuesday we have a cup final and on Saturday we have another."
Koke scored the winner in Atletico's 2-1 win over Athletic Bilbao at the weekend.