The Wales international has been compared to La Liga giants Cristiano Ronaldo and Lionel Messi following Monday night's 3-2 win over West Ham United for Spurs, in which Bale netted his 12th goal in 13 matches for the Premier League outfit.
The 23-year-old is expected to go up against Jack Wilshere, who has been a standout player for the Gunners during a tumultuous few weeks that has included their exit from the FA Cup and suffering a damaging 3-1 defeat to Bayern Munich in the first leg of their round-of-16 Champions League tie.
Despite their recent woes, Arsenal managed to clinch a 2-1 victory over Aston Villa last weekend, placing them fifth in the table, four points adrift of Spurs, who leapfrogged Chelsea this week into third.
Possible starting lineups
Tottenham: Lloris; Walker, Dawson, Vertonghen, Assou-Ekotto; Parker, Dembele; Lennon, Bale, Holtby; Adebayor
Arsenal: Szczesny; Koscielny, Mertesacker, Vermaelen, Jenkinson; Arteta, Wilshere; Walcott, Cazorla, Podolski; Giroud
Sports Mole says: 2-1