The two rivals meet at the Emirates tomorrow lunchtime in a match that often evokes heated exchanges on the pitch and in the stands.
Last season saw alleged abuse aimed at Emmanuel Adebayor by Arsenal fans while Spurs fans responded by chanted offensive songs at Arsene Wenger, but both clubs have said that a repeat of such behaviour will not be tolerated.
"Both clubs are actively encouraging all fans to focus on getting behind their team and enjoying what promises to be a great match on Saturday. A North London derby is always a special occasion and we hope Saturday's match will be remembered for both the action on the pitch, as well as the positive support for both teams off it," read a statement on both clubs' official websites.
"All fans should be aware that breaches of stadium regulations - including anti-social behaviour - will not be tolerated. Arsenal and Tottenham do not tolerate discrimination of any sort, whether it be on the pitch or in the stands.
"If you experience any form of discrimination during a matchday at Emirates Stadium, please use our text service to report the incident, locate the block and, if you are able, the row and seat details. Text 67777 or contact a matchday steward. Both clubs are actively encouraging all fans to focus on getting behind their team and enjoying what promises to be a great match on Saturday."
Arsenal currently sit one point and one place behind their North London rivals in the Premier League table.