The Gunners scored twice in the final moments to lead 2-1 in the third-round match, but a last-minute strike from Danny Graham meant that the two sides must now do battle in London for a place in the latter stages of the competition.
The home side enter the match having suffered their first defeat in five matches against Manchester City on Sunday, but Swansea continued their five-match unbeaten run in all competitions with an impressive point at Everton.
Swansea have also won two of the last four matches between the two sides, drawing once and suffering one defeat. The last time they travelled to the Emirates, Michu was twice on target as the Welsh club recorded a 2-0 victory.
Arsenal will still be without Mikel Arteta for the match, but Kieran Gibbs and Jack Wilshere have both shaken off knocks and are expected to start. Swansea, meanwhile, could start with Graham in the striking role, allowing Michu to operate from a deeper position.
Swansea City: WDDWD
Arsenal: Szczesny; Sanga, Mertesacker, Vermaelen, Gibbs; Ramsey, Cazorla, Wilshere; Walcott, Giroud, Oxlade-Chamberlain
Swansea City: Vorm; Tiendalli, Williams, Chico, Davies; Britton, De Guzman; Hernandez, Michu, Routledge; Graham
Sports Mole says: 2-1