The Serbian, who has scored 10 goals in 15 Belgian league appearances, has to make do with a place on the bench, while Fabrice N'Sakala is still not fit enough to return following a recent knee ligament injury.
Anderlecht: Proto, Deschacht, Mbemba, Vanden Borre, Praet, Defour, Tielemans, Najar, Cyriac, Acheampong, Conte
Subs: Roef, Suarez, Colin, Kljestan, Dendoncker, Kabasele, Mitrovic
Arsenal: Martinez, Chambers, Mertesacker, Monreal, Gibbs, Flamini, Sanchez, Wilshere, Ramsey, Cazorla, Welbeck
Subs: Huddart, Bellerin, Rosicky, Arteta, Oxlade-Chamberlain, Podolski, Campbell
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