The 19-year-old, who has played just 26 minutes of first-team football for the Gunners, is included with Mathieu Debuchy out with an ankle injury and Calum Chambers struggling with a bout of tonsillitis.
However, there's no place for midfielder Shinji Kagawa, who recently returned to Dortmund after a disappointing spell with Manchester United.
ARSENAL XI: Szczesny, Bellerin, Koscielny, Mertesacker, Gibbs, Arteta, Wilshere, Ramsey, Alexis, Ozil, Welbeck
Subs: Ospina, Chambers, Rosicky, Oxlade-Chamberlain, Cazorla, Campbell, Podolski
BORUSSIA DORTMUND XI: Weidenfeller, Durm, Sokratis, Subotic, Schmelzer, Bender, Kehl, Großkreutz, Aubameyang, Mkhitaryan, Immobile
Subs: Langerak, Bandowski, Ginter, Jojic, Amini, Kagawa, Ramos
You can keep track of the match in Germany by following Sports Mole's live commentary.