The two heavyweights fight for the British and Commonwealth titles on October 13 and Price believes that the stakes are high for him against the 40-year-old.
"The general perception of Audley Harrison within the public, unfortunately for him, is not a very good one," Price said. "If I were to lose then my reputation would potentially be in tatters."
"I've got a lot to lose, so I'm going to be so determined the fight goes my way that there's no other possible outcome."
Price is reportedly targeting a bout against Michael Grant following his meeting with Harrison.