San Francisco 49ers defeat St Louis Rams 35-11 at Edward Jones Dome, Missouri.
San Francisco 49ers have trounced NFC West rivals St Louis Rams 35-11 at Edward Jones Dome.
The home side were first on the board when Greg Zuerlein's kick sailed between the posts midway through the first quarter, which was enough for a 3-0 lead heading into the second.
However, the visitors began to pull away before half time, with Anquan Boldin showing great athleticism in scoring the first touchdown of the evening after being found by Colin Kaepernick.
An 11-point lead was established before half time as Frank Gore ran in a 34-yard touchdown.
Kaepernick threw another touchdown pass to Vernon Davis in the third quarter, which saw Jim Harbaugh's men open up a 19-point cushion by the fourth quarter.
Anthony Dixon ran in a one-yard touchdown before the Rams finally scored one of their own thanks to Sam Bradford's pass to Lance Kendricks.
The 49ers had the final say, though, as Kendall Hunter ran the ball in from 29 yards to seal a crushing victory.
Half-Time Report: 49ers lead the Rams at half time >