The 49ers got off to an excellent start when Aaron Lynch blocked a punt from Pat O'Donnell and the home side took over on Chicago's eight-yard line. Colin Kaepernick then found Michael Crabtree in the endzone in the flat for a three-yard score.
Jim Harbaugh's men extended their advantage as Kaepernick led his side on a long drive into Bears territory, but they could not add another touchdown and were forced to settle for a 27-yard field goal from Phil Dawson.
The home side thought that they had added another seven points when Frank Gore broke free down the middle and raced into the endzone for the score, but it was called back for a holding penalty. However, Gore did score on the next drive with an eight-yard run for a touchdown.
Chicago were struggling to get anything going on offense until they pulled a score back right before the break, as Jay Cutler lofted the ball into the endzone, and Brandon Marshall pulled off an impressive one-handed catch for the score.