The Eagles upstaged the much-publicised return of Redskins quarterback Robert Griffin III by playing the match at a frenetic pace, taking a 26-point lead in the first quarter before holding off a late fightback to claim a 33-27 victory.
The Eagles finished bottom of the NFC East last season with just four wins to their name, and owner Lurie was delighted at having got the new season off to a winning start against last year's NFC East champions.
"You have great dreams and you have nightmares. That was a great dream," Lurie told The AP.
The match was Eagles coach Chip Kelly's first game in charge of an NFL side.