The Giants are 3-4 so far this season and trail both the Dallas Cowboys and Philadelphia Eagles by two games in the NFC East.
"This is like the playoffs for us," Pierre-Paul said, according to Newsday.
"We gotta win, basically. We gotta win... [the playoffs] have started."
New York have needed winning streaks to get into the playoffs during their two most recent Super Bowl runs, and Pierre-Paul has issued the rallying cry ahead of their encounter with the Indianapolis Colts on Monday night.