The AFC North side, who face the New England Patriots this weekend, have recorded nine sacks in their first four games this season.
The Patriots quarterback told reporters: "They can rush the quarterback. They have guys at all four spots that can rush and then when they bring the backups in, those guys rush.
"It's really unique in that pretty much whoever is in there can get an edge on a guy, can get to the quarterback, force the ball out quickly. That's why they have one of the best defenses in the league.
"They're 2-0 at home. They play well, they're good. I know the guys on defense really respect that offense and what they're able to do. They're explosive. We have to do our part as an offense to try to keep their offense off the field as well as going and scoring points."
Brady has completed 1,014 passing yards so far this season.