The Jaguars have signed up to play one home game at Wembley Stadium every year until the 2016 season, and have been mooted as the one of the franchises that could be relocated should the NFL expand into the United Kingdom permanently.
"London is a very, very important thing for Jacksonville," Khan told reporters. "Financially, exposure-wise, the awareness we have for the team, it's amazing.
"The merchandise we sold in London, the kind of Jaguars stuff you see over there you have to get out there. Eventually, it's wins and losses, but it's much more than that."
Gus Bradley's side lost in their clash with the San Francisco 49ers at Wembley last season.