LaVon Brazill has been suspended for the first four games of the 2013 NFL season after violating the league's policy on substances of abuse.
The Indianapolis Colts wide receiver will be eligible to return to the team at the end of September.
Following the announcement, the 24-year-old tweeted: "Minor setback for a major comeback. Still got a smile on my face. It's in da past movin forward."
Brazill made just 11 receptions for the Colts in 2012, recording 186 receiving yards and scoring a touchdown.