The Houston Texans used their first-round pick in this year's Draft to acquire the former Clemson wideout.
The quarterback told the team's website: "I'm very excited about all the picks. Obviously, being an offensive guy, to get a weapon like DeAndre early in the Draft, very excited to get him here and work with him and bring him along because he can really help us and add a dimension to our offensive game.
"You see some of the games and you see the explosiveness, what he can bring to an offense, run after catch, his ability to go up and catch the football in traffic. Just very excited about his playmaking ability, and his tough-minded nature of how he plays.
"Some of the linemen we've taken and all the other guys on the defensive side can really help us. Very pleased with how Coach [Gary] Kubiak and [general manager] Rick [Smith] and all the guys upstairs handled the draft for us."
Hopkins had 1,405 receiving yards and 18 touchdowns during the 2012 college season.