Matthews required two separate operations to fix a broken thumb which he sustained last season, which resulted in him missing six games, including two playoff clashes.
The 27-year-old told USA Today: "Obviously, OTAs will probably be one thing and I can't imagine I'll be too heavily involved with some of the stuff. I'm sure I can do stuff here and there. But yeah, we risked it once, and unfortunately, it didn't pay off.
"Quite honestly, I clubbed it up last season, and I was just a number out there, because we didn't have enough people to suit up against Philadelphia. It was by far my worst professional game, but there was a legitimate excuse."
Matthews, who averages 10 sacks per season through his five years in the NFL, stated that he expects to be back in time for training camp in July.