The NFC West side travel to their divisional rivals later today, with both teams holding 3-2 records heading into the NFL clash.
The wide receiver told the Cardinals' official website: "If we could win only one game in the division, it would definitely be the 49ers.
"That's just the way it's been around here for years. It's going to be the toughest game. We understand the road to winning the NFC West goes through San Francisco."
Defensive tackle Darnell Dockett added: "Everybody says it's just another game but if you've been here for history, it's not just another game. It's a game where you have to put your big-boy pads on."
Both teams are on two-game winning streaks ahead of today's meeting.